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Clinical holds are not uncommon, and it’s unclear how long AstraZeneca’s might last. But the progress of the company’s trial — and those of all Covid-19 vaccines in development — are being closely watched given the pressing need for new ways to curb the global pandemic. There are currently nine vaccine candidates in Phase 3 trials. AstraZeneca’s is the first Phase 3 Covid-19 vaccine trial known to have been put on hold. This SAE is a pretty uncommon immune response. The odds of this particular reaction happening randomly are about .3%. There however are many similar low probability events. What is the total percentage of these though?

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